Cargando…

Chronic stepwise cerebral hypoperfusion differentially induces synaptic proteome changes in the frontal cortex, occipital cortex, and hippocampus in rats

During chronic cerebral hypoperfusion (CCH), the cerebral blood flow gradually decreases, leading to cognitive impairments and neurodegenerative disorders, such as vascular dementia. The reduced oxygenation, energy supply induced metabolic changes, and insufficient neuroplasticity could be reflected...

Descripción completa

Detalles Bibliográficos
Autores principales: Tukacs, Vanda, Mittli, Dániel, Györffy, Balázs András, Hunyady-Gulyás, Éva, Hlatky, Dávid, Tóth, Vilmos, Ravasz, Lilla, Medzihradszky, F. Katalin, Nyitrai, Gabriella, Czurkó, András, Juhász, Gábor, Kardos, József, Kékesi, Katalin Adrienna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524772/
https://www.ncbi.nlm.nih.gov/pubmed/32994510
http://dx.doi.org/10.1038/s41598-020-72868-w