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Polygenic risk score opportunities for early detection and prevention strategies in endometrial cancer

Recent large-scale genetic studies, particularly genome-wide association studies (GWAS), have emphasised the importance of common genetic variation in endometrial cancer susceptibility. Although each of these variants only confer modest effects on endometrial cancer risk, together they are likely to...

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Detalles Bibliográficos
Autores principales: O’Mara, Tracy A., Crosbie, Emma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524798/
https://www.ncbi.nlm.nih.gov/pubmed/32624578
http://dx.doi.org/10.1038/s41416-020-0959-7