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Cancer-associated fibroblasts mediate cancer progression and remodel the tumouroid stroma

BACKGROUND: Cancer-associated fibroblasts (CAFs) are highly differentiated and heterogeneous cancer-stromal cells that promote tumour growth, angiogenesis and matrix remodelling. METHODS: We utilised an adapted version of a previously developed 3D in vitro model of colorectal cancer, composed of a c...

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Detalles Bibliográficos
Autores principales:	Pape, Judith, Magdeldin, Tarig, Stamati, Katerina, Nyga, Agata, Loizidou, Marilena, Emberton, Mark, Cheema, Umber
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524802/ https://www.ncbi.nlm.nih.gov/pubmed/32641866 http://dx.doi.org/10.1038/s41416-020-0973-9

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