Cargando…

Favorable therapeutic response after anti-Mesothelin antibody–drug conjugate treatment requires high expression of Mesothelin in tumor cells

PURPOSE: The cell surface glycoprotein Mesothelin is overexpressed in ovarian, fallopian tube, endometrial, cervical and primary peritoneal cancer and, therefore, might become a particular interesting tumor target in gynecologic oncology. However, even in malignant tumors of the same entity the leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Lazzerini, Lea, Jöhrens, Korinna, Sehouli, Jalid, Cichon, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524828/
https://www.ncbi.nlm.nih.gov/pubmed/32815024
http://dx.doi.org/10.1007/s00404-020-05734-9