Arterial endoglin does not protect against arteriovenous malformations

INTRODUCTION: Endoglin (ENG) forms a receptor complex with ALK1 in endothelial cells (ECs) to promote BMP9/10 signalling. Loss of function mutations in either ENG or ALK1 genes lead to the inherited vascular disorder hereditary haemorrhagic telangiectasia (HHT), characterised by arteriovenous malfor...

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Detalles Bibliográficos
Autores principales: Singh, Esha, Redgrave, Rachael E., Phillips, Helen M., Arthur, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524831/
https://www.ncbi.nlm.nih.gov/pubmed/32506200
http://dx.doi.org/10.1007/s10456-020-09731-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524831/
https://www.ncbi.nlm.nih.gov/pubmed/32506200
http://dx.doi.org/10.1007/s10456-020-09731-z

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