Role of the IL-2 inducible tyrosine kinase ITK and its inhibitors in disease pathogenesis

ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines. Studie...

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Detalles Bibliográficos
Autores principales: Lechner, Kristina S., Neurath, Markus F., Weigmann, Benno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524833/
https://www.ncbi.nlm.nih.gov/pubmed/32808093
http://dx.doi.org/10.1007/s00109-020-01958-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524833/
https://www.ncbi.nlm.nih.gov/pubmed/32808093
http://dx.doi.org/10.1007/s00109-020-01958-z

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