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Pannexin-1 channel “fuels” by releasing ATP from bone marrow cells a state of sterile inflammation required for optimal mobilization and homing of hematopoietic stem cells

An efficient harvest of hematopoietic stem/progenitor cells (HSPCs) after pharmacological mobilization from the bone marrow (BM) into peripheral blood (PB) and subsequent proper homing and engraftment of these cells are crucial for clinical outcomes from hematopoietic transplants. Since extracellula...

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Detalles Bibliográficos
Autores principales: Cymer, Monika, Brzezniakiewicz-Janus, Katarzyna, Bujko, Kamila, Thapa, Arjun, Ratajczak, Janina, Anusz, Krzysztof, Tracz, Michał, Jackowska-Tracz, Agnieszka, Ratajczak, Mariusz Z., Adamiak, Mateusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524928/
https://www.ncbi.nlm.nih.gov/pubmed/32533388
http://dx.doi.org/10.1007/s11302-020-09706-1