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Pannexin-1 channel “fuels” by releasing ATP from bone marrow cells a state of sterile inflammation required for optimal mobilization and homing of hematopoietic stem cells
An efficient harvest of hematopoietic stem/progenitor cells (HSPCs) after pharmacological mobilization from the bone marrow (BM) into peripheral blood (PB) and subsequent proper homing and engraftment of these cells are crucial for clinical outcomes from hematopoietic transplants. Since extracellula...
Autores principales: | Cymer, Monika, Brzezniakiewicz-Janus, Katarzyna, Bujko, Kamila, Thapa, Arjun, Ratajczak, Janina, Anusz, Krzysztof, Tracz, Michał, Jackowska-Tracz, Agnieszka, Ratajczak, Mariusz Z., Adamiak, Mateusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524928/ https://www.ncbi.nlm.nih.gov/pubmed/32533388 http://dx.doi.org/10.1007/s11302-020-09706-1 |
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