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[(11)C]mHED PET follows a two-tissue compartment model in mouse myocardium with norepinephrine transporter (NET)-dependent uptake, while [(18)F]LMI1195 uptake is NET-independent

PURPOSE: Clinical positron emission tomography (PET) imaging of the presynaptic norepinephrine transporter (NET) function provides valuable diagnostic information on sympathetic outflow and neuronal status. As data on the NET-targeting PET tracers [(11)C]meta-hydroxyephedrine ([(11)C]mHED) and [(18)...

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Detalles Bibliográficos
Autores principales: Mu, Linjing, Krämer, Stefanie D., Warnock, Geoffrey I., Haider, Ahmed, Bengs, Susan, Cartolano, Giovanni, Bräm, Dominic S., Keller, Claudia, Schibli, Roger, Ametamey, Simon M., Kaufmann, Philipp A., Gebhard, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524946/
https://www.ncbi.nlm.nih.gov/pubmed/32990788
http://dx.doi.org/10.1186/s13550-020-00700-7