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Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model

PURPOSE: The reoperation rate for breast-conserving surgery is as high as 15–30% due to residual tumor in the surgical cavity after surgery. In vivo tumor-targeted optical molecular imaging may serve as a red-flag technique to improve intraoperative surgical margin assessment and to reduce reoperati...

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Detalles Bibliográficos
Autores principales: Suurs, Frans V., Qiu, Si-Qi, Yim, Joshua J., Schröder, Carolien P., Timmer-Bosscha, Hetty, Bensen, Eric S., Santini, John T., de Vries, Elisabeth G. E., Bogyo, Matthew, van Dam, Gooitzen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524956/
https://www.ncbi.nlm.nih.gov/pubmed/32990883
http://dx.doi.org/10.1186/s13550-020-00688-0