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Paramagnetic Metal Accumulation in the Deep Gray Matter Nuclei Is Associated With Neurodegeneration in Wilson’s Disease

BACKGROUND: Neuropathological studies have revealed copper and iron accumulation in the deep gray matter (DGM) nuclei of patients with Wilson’s disease (WD). However, the association between metal accumulation and neurodegeneration in WD has not been well studied in vivo. The study was aimed to inve...

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Detalles Bibliográficos
Autores principales: Yuan, Xiang-Zhen, Li, Gai-Ying, Chen, Jia-Lin, Li, Jian-Qi, Wang, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525019/
https://www.ncbi.nlm.nih.gov/pubmed/33041766
http://dx.doi.org/10.3389/fnins.2020.573633