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Paramagnetic Metal Accumulation in the Deep Gray Matter Nuclei Is Associated With Neurodegeneration in Wilson’s Disease
BACKGROUND: Neuropathological studies have revealed copper and iron accumulation in the deep gray matter (DGM) nuclei of patients with Wilson’s disease (WD). However, the association between metal accumulation and neurodegeneration in WD has not been well studied in vivo. The study was aimed to inve...
Autores principales: | Yuan, Xiang-Zhen, Li, Gai-Ying, Chen, Jia-Lin, Li, Jian-Qi, Wang, Xiao-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525019/ https://www.ncbi.nlm.nih.gov/pubmed/33041766 http://dx.doi.org/10.3389/fnins.2020.573633 |
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