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Staphylococcus epidermidis Boosts Innate Immune Response by Activation of Gamma Delta T Cells and Induction of Perforin-2 in Human Skin

Perforin-2 (P-2) is an antimicrobial protein with unique properties to kill intracellular bacteria. Gamma delta (GD) T cells, as the major T cell population in epithelial tissues, play a central role in protective and pathogenic immune responses in the skin. However, the tissue-specific mechanisms t...

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Detalles Bibliográficos
Autores principales: Pastar, Irena, O’Neill, Katelyn, Padula, Laura, Head, Cheyanne R., Burgess, Jamie L., Chen, Vivien, Garcia, Denisse, Stojadinovic, Olivera, Hower, Suzanne, Plano, Gregory V., Thaller, Seth R., Tomic-Canic, Marjana, Strbo, Natasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525037/
https://www.ncbi.nlm.nih.gov/pubmed/33042139
http://dx.doi.org/10.3389/fimmu.2020.550946