Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor

The oncolytic adenovirus (Adv) exhibited poor infection efficiency in tumor cells with low coxsackie and adenovirus receptor (CAR) on the cell surface, which limits the therapeutic efficacy of the Adv-mediated cancer gene therapy. In addition, the abundant adenovirus neutralizing antibodies also abr...

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Detalles Bibliográficos
Autores principales: Zhang, Yonghui, Wu, Junyi, Zhang, Hailin, Wei, Jiwu, Wu, Junhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525182/
https://www.ncbi.nlm.nih.gov/pubmed/33042975
http://dx.doi.org/10.3389/fbioe.2020.574007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525182/
https://www.ncbi.nlm.nih.gov/pubmed/33042975
http://dx.doi.org/10.3389/fbioe.2020.574007

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