Harnessing endogenous repair mechanisms for targeted gene knock-in of bovine embryos

Introducing useful traits into livestock breeding programs through gene knock-ins has proven challenging. Typically, targeted insertions have been performed in cell lines, followed by somatic cell nuclear transfer cloning, which can be inefficient. An alternative is to introduce genome editing reage...

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Detalles Bibliográficos
Autores principales: Owen, Joseph R., Hennig, Sadie L., McNabb, Bret R., Lin, Jason C., Young, Amy E., Murray, James D., Ross, Pablo J., Van Eenennaam, Alison L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525238/
https://www.ncbi.nlm.nih.gov/pubmed/32994506
http://dx.doi.org/10.1038/s41598-020-72902-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525238/
https://www.ncbi.nlm.nih.gov/pubmed/32994506
http://dx.doi.org/10.1038/s41598-020-72902-x

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