APPA (apocynin and paeonol) modulates pathological aspects of human neutrophil function, without supressing antimicrobial ability, and inhibits TNFα expression and signalling

Neutrophils are key players in the pathophysiological process underlying inflammatory conditions not only by release of tissue-damaging cytotoxic enzymes, reactive oxygen species (ROS) but also by secretion of important immunomodulatory chemokines and cytokines. Here, we report the effects of the no...

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Detalles Bibliográficos
Autores principales: Cross, A. L., Hawkes, J., Wright, H. L., Moots, R. J., Edwards, S. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525285/
https://www.ncbi.nlm.nih.gov/pubmed/32383062
http://dx.doi.org/10.1007/s10787-020-00715-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525285/
https://www.ncbi.nlm.nih.gov/pubmed/32383062
http://dx.doi.org/10.1007/s10787-020-00715-5

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