EPS8 phosphorylation by Src modulates its oncogenic functions

BACKGROUND: EPS8 is a scaffolding protein that regulates proliferation, actin dynamics and receptor trafficking. Its expression is increased in cancer, enhancing mitogenesis, migration and tumorigenesis. Src phosphorylates EPS8 at four tyrosine residues, although the function is unknown. Here we inv...

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Detalles Bibliográficos
Autores principales: Shahoumi, Linah A., Khodadadi, Hesam, Bensreti, Husam, Baban, Babak, Yeudall, W. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525440/
https://www.ncbi.nlm.nih.gov/pubmed/32641864
http://dx.doi.org/10.1038/s41416-020-0976-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525440/
https://www.ncbi.nlm.nih.gov/pubmed/32641864
http://dx.doi.org/10.1038/s41416-020-0976-6

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