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Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model

BACKGROUND: Radiotherapy enhances innate and adaptive anti-tumour immunity. It is unclear whether this effect may be harnessed by combining immunotherapy with radiotherapy fractions used to treat prostate cancer. We investigated tumour immune microenvironment responses of pre-clinical prostate cance...

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Detalles Bibliográficos
Autores principales: Philippou, Yiannis, Sjoberg, Hanna T., Murphy, Emma, Alyacoubi, Said, Jones, Keaton I., Gordon-Weeks, Alex N., Phyu, Su, Parkes, Eileen E., Gillies McKenna, W., Lamb, Alastair D., Gileadi, Uzi, Cerundolo, Vincenzo, Scheiblin, David A., Lockett, Stephen J., Wink, David A., Mills, Ian G., Hamdy, Freddie C., Muschel, Ruth J., Bryant, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525450/
https://www.ncbi.nlm.nih.gov/pubmed/32641865
http://dx.doi.org/10.1038/s41416-020-0956-x