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Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
BACKGROUND: Radiotherapy enhances innate and adaptive anti-tumour immunity. It is unclear whether this effect may be harnessed by combining immunotherapy with radiotherapy fractions used to treat prostate cancer. We investigated tumour immune microenvironment responses of pre-clinical prostate cance...
Autores principales: | Philippou, Yiannis, Sjoberg, Hanna T., Murphy, Emma, Alyacoubi, Said, Jones, Keaton I., Gordon-Weeks, Alex N., Phyu, Su, Parkes, Eileen E., Gillies McKenna, W., Lamb, Alastair D., Gileadi, Uzi, Cerundolo, Vincenzo, Scheiblin, David A., Lockett, Stephen J., Wink, David A., Mills, Ian G., Hamdy, Freddie C., Muschel, Ruth J., Bryant, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525450/ https://www.ncbi.nlm.nih.gov/pubmed/32641865 http://dx.doi.org/10.1038/s41416-020-0956-x |
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