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Antibodies from Sierra Leonean and Nigerian Lassa fever survivors cross-react with recombinant proteins representing Lassa viruses of divergent lineages

Lassa virus (LASV) is the causative agent of Lassa fever, an often-fatal hemorrhagic disease that is endemic in West Africa. Seven genetically distinct LASV lineages have been identified. As part of CEPI’s (Coalition for Epidemic Preparedness Innovations) Lassa vaccine development program, we assess...

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Detalles Bibliográficos
Autores principales: Heinrich, Megan L., Boisen, Matthew L., Nelson, Diana K. S., Bush, Duane J., Cross, Robert W., Koval, Anatoliy P., Hoffmann, Andrew R., Beddingfield, Brandon J., Hastie, Kathryn M., Rowland, Megan M., Aimukanova, Irina, Koval, Sophia, Lathigra, Raju, Borisevich, Viktoriya, Momoh, Mambu, Sandi, John Demby, Goba, Augustine, Odia, lkponmwosa, Baimba, Francis, Aiyepada, John O., Ebo, Benevolence, Eromon, Philomena, Ugwu, Chinedu, Folarin, Onikepe, Olumade, Testimony, Onyechi, MacDonald N., Etafo, Johnson, Adeyemi, Rashidat, Ella, Elijah E., Aminu, Maryam, Gomerep, Simji S., Eke, Matthew Afam, Ogunsanya, Olusola, Akpede, George O., Asogun, Danny O., Okogbenin, Sylvanus A., Okokhere, Peter O., Holst, Johan, Shaffer, Jeffrey G., Schieffelin, John S., Geisbert, Thomas W., Saphire, Erica Ollmann, Happi, Christian T., Grant, Donald S., Garry, Robert F., Branco, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525497/
https://www.ncbi.nlm.nih.gov/pubmed/32994446
http://dx.doi.org/10.1038/s41598-020-72539-w