Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

The CRISPR-Cas9 system has increased the speed and precision of genetic editing in cells and animals. However, model generation for drug development is still expensive and time-consuming, demanding more target flexibility and faster turnaround times with high reproducibility. The generation of a tig...

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Detalles Bibliográficos
Autores principales: Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525522/
https://www.ncbi.nlm.nih.gov/pubmed/32994412
http://dx.doi.org/10.1038/s41467-020-18548-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525522/
https://www.ncbi.nlm.nih.gov/pubmed/32994412
http://dx.doi.org/10.1038/s41467-020-18548-9

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