Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis

The orexigenic peptide ghrelin (Ghr) stimulates hunger signals in the hypothalamus via growth hormone secretagogue receptor (GHS-R1a). Gastric Ghr is synthetized as a preprohormone which is proteolytically cleaved, and acylated by a membrane-bound acyl transferase (MBOAT). Circulating Ghr is reduced...

Descripción completa

Detalles Bibliográficos
Autores principales: Petrescu, Anca D., Grant, Stephanie, Williams, Elaina, Frampton, Gabriel, Reinhart, Evan H., Nguyen, Amy, An, Suyeon, McMillin, Matthew, DeMorrow, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525536/
https://www.ncbi.nlm.nih.gov/pubmed/32994489
http://dx.doi.org/10.1038/s41598-020-72681-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525536/
https://www.ncbi.nlm.nih.gov/pubmed/32994489
http://dx.doi.org/10.1038/s41598-020-72681-5

Ejemplares similares