CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer

BACKGROUND: Toward identifying new strategies to target gastric cancer stem-like cells (CSCs), we evaluated the function of the tumour suppressor CDK5 regulatory subunit-associated protein 3 (CDK5RAP3) in gastric CSC maintenance. METHODS: We examined the expression of CDK5RAP3 and CD44 in gastric ca...

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Detalles Bibliográficos
Autores principales: Lin, Jian-xian, Yoon, Changhwan, Li, Ping, Ryeom, Sandra W., Cho, Soo-Jeong, Zheng, Chao-hui, Xie, Jian-wei, Wang, Jian-bin, Lu, Jun, Chen, Qi-yue, Yoon, Sam S., Huang, Chang-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525566/
https://www.ncbi.nlm.nih.gov/pubmed/32606358
http://dx.doi.org/10.1038/s41416-020-0963-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525566/
https://www.ncbi.nlm.nih.gov/pubmed/32606358
http://dx.doi.org/10.1038/s41416-020-0963-y

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