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Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin

Men consume the most nicotine and cannabis products but impacts on sperm epigenetics are poorly characterized. Evidence suggests that preconception exposure to these drugs alters offspring neurodevelopment. Epigenetics may in part facilitate heritability. We therefore compared effects of exposure to...

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Detalles Bibliográficos
Autores principales: Schrott, Rose, Rajavel, Maya, Acharya, Kelly, Huang, Zhiqing, Acharya, Chaitanya, Hawkey, Andrew, Pippen, Erica, Lyerly, H. Kim, Levin, Edward D., Murphy, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525661/
https://www.ncbi.nlm.nih.gov/pubmed/32994467
http://dx.doi.org/10.1038/s41598-020-72783-0