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On the Role of the Objective in the Optimization of Compartmental Models for Biomedical Therapies
We review and discuss results obtained through an application of tools of nonlinear optimal control to biomedical problems. We discuss various aspects of the modeling of the dynamics (such as growth and interaction terms), modeling of treatment (including pharmacometrics of the drugs), and give spec...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525767/ https://www.ncbi.nlm.nih.gov/pubmed/33012845 http://dx.doi.org/10.1007/s10957-020-01754-2 |