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On the Role of the Objective in the Optimization of Compartmental Models for Biomedical Therapies

We review and discuss results obtained through an application of tools of nonlinear optimal control to biomedical problems. We discuss various aspects of the modeling of the dynamics (such as growth and interaction terms), modeling of treatment (including pharmacometrics of the drugs), and give spec...

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Detalles Bibliográficos
Autores principales: Ledzewicz, Urszula, Schättler, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525767/
https://www.ncbi.nlm.nih.gov/pubmed/33012845
http://dx.doi.org/10.1007/s10957-020-01754-2