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An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration

Directional cell migration drives embryonic development, cancer metastasis, and tissue repair and regeneration. Here, we examine the role of intraflagellar transport (IFT) 20 (Ift20) during polarized migration of epidermal cells. IFT20 is implicated in regulating cell migration independently of the...

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Detalles Bibliográficos
Autores principales: Su, Steven, Begum, Salma, Ezratty, Ellen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525813/
https://www.ncbi.nlm.nih.gov/pubmed/32520638
http://dx.doi.org/10.1091/mbc.E20-04-0232