Cargando…
An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration
Directional cell migration drives embryonic development, cancer metastasis, and tissue repair and regeneration. Here, we examine the role of intraflagellar transport (IFT) 20 (Ift20) during polarized migration of epidermal cells. IFT20 is implicated in regulating cell migration independently of the...
Autores principales: | Su, Steven, Begum, Salma, Ezratty, Ellen J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525813/ https://www.ncbi.nlm.nih.gov/pubmed/32520638 http://dx.doi.org/10.1091/mbc.E20-04-0232 |
Ejemplares similares
-
Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells
por: Ezratty, Ellen J., et al.
Publicado: (2009) -
LAPTM4B‐35 promotes cancer cell migration via stimulating integrin beta1 recycling and focal adhesion dynamics
por: Liu, Minxia, et al.
Publicado: (2022) -
Robust interaction of IFT70 with IFT52–IFT88 in the IFT-B complex is required for ciliogenesis
por: Takei, Ryota, et al.
Publicado: (2018) -
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration
por: Mostafavi-Pour, Zohreh, et al.
Publicado: (2003) -
Focal adhesions are sites of integrin extension
por: Askari, Janet A., et al.
Publicado: (2010)