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HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer
The positive transcription elongation factor b (P-TEFb), composed of CDK9 and cyclin T, stimulates transcriptional elongation by RNA polymerase (Pol) II and regulates cell growth and differentiation. Recently, we demonstrated that P-TEFb also controls the expression of EMT regulators to promote brea...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525814/ https://www.ncbi.nlm.nih.gov/pubmed/32520633 http://dx.doi.org/10.1091/mbc.E19-12-0704 |