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Centrosomes are required for proper β-catenin processing and Wnt response

The Wnt/β-catenin signaling pathway is central to metazoan development and routinely dysregulated in cancer. Wnt/β-catenin signaling initiates transcriptional reprogramming upon stabilization of the transcription factor β-catenin, which is otherwise posttranslationally processed by a destruction com...

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Detalles Bibliográficos
Autores principales: Vora, Setu M., Fassler, Jan S., Phillips, Bryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525817/
https://www.ncbi.nlm.nih.gov/pubmed/32583737
http://dx.doi.org/10.1091/mbc.E20-02-0139