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Multisite phosphorylation determines the formation of Ska–Ndc80 macro-complexes that are essential for chromosome segregation during mitosis

The human Ska complex (Ska) localizing to both spindle microtubules and kinetochores is essential for proper chromosome segregation during mitosis. Although several mechanisms have been proposed to explain how Ska is recruited to kinetochores, it is still not fully understood. By analyzing Ska3 phos...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Hu, Liqiao, Chen, Yujue, Tian, Wei, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525821/
https://www.ncbi.nlm.nih.gov/pubmed/32491969
http://dx.doi.org/10.1091/mbc.E19-10-0569