Retargeting azithromycin analogues to have dual-modality antimalarial activity

BACKGROUND: Resistance to front-line antimalarials (artemisinin combination therapies) is spreading, and development of new drug treatment strategies to rapidly kill Plasmodium spp. malaria parasites is urgently needed. Azithromycin is a clinically used macrolide antibiotic proposed as a partner dru...

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Detalles Bibliográficos
Autores principales: Burns, Amy L., Sleebs, Brad E., Siddiqui, Ghizal, De Paoli, Amanda E., Anderson, Dovile, Liffner, Benjamin, Harvey, Richard, Beeson, James G., Creek, Darren J., Goodman, Christopher D., McFadden, Geoffrey I., Wilson, Danny W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526119/
https://www.ncbi.nlm.nih.gov/pubmed/32993629
http://dx.doi.org/10.1186/s12915-020-00859-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526119/
https://www.ncbi.nlm.nih.gov/pubmed/32993629
http://dx.doi.org/10.1186/s12915-020-00859-4

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