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Identification and validation of methylation-driven genes prognostic signature for recurrence of laryngeal squamous cell carcinoma by integrated bioinformatics analysis

BACKGROUND: Recurrence remains a major obstacle to long-term survival of laryngeal squamous cell carcinoma (LSCC). We conducted a genome-wide integrated analysis of methylation and the transcriptome to establish methylation-driven genes prognostic signature (MDGPS) to precisely predict recurrence pr...

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Detalles Bibliográficos
Autores principales: Cui, Jie, Wang, Liping, Zhong, Waisheng, Chen, Zhen, Chen, Jie, Yang, Hong, Liu, Genglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526132/
https://www.ncbi.nlm.nih.gov/pubmed/33005105
http://dx.doi.org/10.1186/s12935-020-01567-3