Deleterious mutations show increasing negative effects with age in Drosophila melanogaster

BACKGROUND: In order for aging to evolve in response to a declining strength of selection with age, a genetic architecture that allows for mutations with age-specific effects on organismal performance is required. Our understanding of how selective effects of individual mutations are distributed acr...

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Detalles Bibliográficos
Autores principales: Brengdahl, Martin I., Kimber, Christopher M., Elias, Phoebe, Thompson, Josephine, Friberg, Urban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526172/
https://www.ncbi.nlm.nih.gov/pubmed/32993647
http://dx.doi.org/10.1186/s12915-020-00858-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526172/
https://www.ncbi.nlm.nih.gov/pubmed/32993647
http://dx.doi.org/10.1186/s12915-020-00858-5

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