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Deleterious mutations show increasing negative effects with age in Drosophila melanogaster
BACKGROUND: In order for aging to evolve in response to a declining strength of selection with age, a genetic architecture that allows for mutations with age-specific effects on organismal performance is required. Our understanding of how selective effects of individual mutations are distributed acr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526172/ https://www.ncbi.nlm.nih.gov/pubmed/32993647 http://dx.doi.org/10.1186/s12915-020-00858-5 |