Cargando…

The evaluation of red blood cell folate and methotrexate levels during protocol M in childhood acute lymphoblastic leukemia

BACKGROUND: After High-Dose Methotrexate (HD-MTX), folinic acid rescue therapy (Leucovorin) is administered to reduce side effects in pediatric acute lymphoblastic leukemia (ALL) patients. Leucovorin and MTX are structural analogues, possibly competing for cellular transport and intracellular metabo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oosterom, N., Fiocco, M., Kloos, R. Q. H., van der Sluis, I. M., Pieters, R., van Zelst, B. D., Smith, D. E. C., van den Heuvel-Eibrink, M. M., de Jonge, R., Heil, S. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526241/ https://www.ncbi.nlm.nih.gov/pubmed/32998716 http://dx.doi.org/10.1186/s12885-020-07422-y

Ejemplares similares

Changes in intracellular folate metabolism during high-dose methotrexate and Leucovorin rescue therapy in children with acute lymphoblastic leukemia
por: Oosterom, Natanja, et al.
Publicado: (2019)

Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia
por: Driehuis, E., et al.
Publicado: (2020)

Correction: Patient-derived oral mucosa organoids as an in vitro model for methotrexate induced toxicity in pediatric acute lymphoblastic leukemia
por: Driehuis, E., et al.
Publicado: (2020)

A decrease in vitamin D levels is associated with methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia
por: Oosterom, N., et al.
Publicado: (2018)

Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia
por: Oosterom, Natanja, et al.
Publicado: (2018)

Recent perspectives on the association between osteonecrosis and bone mineral density decline in childhood acute lymphoblastic leukemia
por: van Atteveld, Jenneke E, et al.
Publicado: (2021)

Effect of post-consolidation regimen on symptomatic osteonecrosis in three DCOG acute lymphoblastic leukemia protocols
por: van Atteveld, Jenneke E., et al.
Publicado: (2021)

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia
por: Wojtuszkiewicz, Anna, et al.
Publicado: (2015)

Dexamethasone-Induced Sarcopenia and Physical Frailty in Children With Acute Lymphoblastic Leukemia: Protocol for a Prospective Cohort Study
por: Verwaaijen, Emma Jacobine, et al.
Publicado: (2022)

Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures
por: Gosselt, Helen R., et al.
Publicado: (2020)

EVI1 expression in childhood acute lymphoblastic leukaemia is not restricted to MLL and BCR/ABL rearrangements and is influenced by age
por: Stevens, A, et al.
Publicado: (2014)

The influence of serum methotrexate concentrations and drug dosage on outcome in childhood acute lymphoblastic leukaemia.
por: Pearson, A. D., et al.
Publicado: (1991)

Unraveling Dexamethasone-Induced Neurobehavioral and Sleep Problems in Children With ALL: Which Determinants Are Important?
por: van Hulst, Annelienke M., et al.
Publicado: (2023)

The utility of a portable muscle ultrasound in the assessment of muscle alterations in children with acute lymphoblastic leukaemia
por: Verwaaijen, Emma J., et al.
Publicado: (2023)

Venous thromboembolism in a large cohort of children with acute lymphoblastic leukemia: Risk factors and effect on prognosis
por: Klaassen, Irene L. M., et al.
Publicado: (2019)

Progress against childhood and adolescent acute lymphoblastic leukaemia in the Netherlands, 1990–2015
por: Reedijk, Ardine M. J., et al.
Publicado: (2020)

The effect of methotrexate on folate metabolism in the rat.
por: Barford, P. A., et al.
Publicado: (1980)

Individualized dosing guidelines for PEGasparaginase and factors influencing the clearance: a population pharmacokinetic model
por: Kloos, Robin Q.H., et al.
Publicado: (2020)

Individualized dosing guidelines for PEGasparaginase and factors influencing the clearance: a population pharmacokinetic model
por: Kloos, Robin Q.H., et al.
Publicado: (2023)

Is folate absorption impaired by high dose methotrexate?
por: Pinkerton, C. R.
Publicado: (1983)

Novel Adaption of the SARC-F Score to Classify Pediatric Hemato-Oncology Patients with Functional Sarcopenia
por: Verwaaijen, Emma J., et al.
Publicado: (2023)

Is asparaginase encapsulated in erythrocytes effective as second‐line treatment in acute lymphoblastic leukaemia?
por: van der Sluis, Inge M., et al.
Publicado: (2022)

Study protocol: DexaDays-2, hydrocortisone for treatment of dexamethasone-induced neurobehavioral side effects in pediatric leukemia patients: a double-blind placebo controlled randomized intervention study with cross-over design
por: van Hulst, A. M., et al.
Publicado: (2021)

Single-nucleotide polymorphisms in the folate pathway are associated with response to methotrexate treatment in juvenile idiopathic arthritis
por: Heijstek, MW, et al.
Publicado: (2008)

Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells
por: Panetta, John C., et al.
Publicado: (2010)

Acute Activation of Metabolic Syndrome Components in Pediatric Acute Lymphoblastic Leukemia Patients Treated with Dexamethasone
por: Warris, Lidewij T., et al.
Publicado: (2016)

High-dose methotrexate vs. Capizzi methotrexate for the treatment of childhood T-cell acute lymphoblastic leukemia
por: Jastaniah, Wasil, et al.
Publicado: (2018)

Can biomarkers be used to improve diagnosis and prediction of metabolic syndrome in childhood cancer survivors? A systematic review
por: Pluimakers, Vincent G., et al.
Publicado: (2021)

Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients
por: Sassen, Sebastiaan D.T., et al.
Publicado: (2017)

Poly(amidoamine) Dendrimer–Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein
por: van Dongen, Mallory A., et al.
Publicado: (2014)

Influence of bisphosphonates or recombinant human parathyroid hormone on in vitro sensitivity of acute lymphoblastic leukemia cells to chemotherapy
por: de Winter, Demi T.C., et al.
Publicado: (2022)

Obesity Is Underestimated Using Body Mass Index and Waist-Hip Ratio in Long-Term Adult Survivors of Childhood Cancer
por: Blijdorp, Karin, et al.
Publicado: (2012)

MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy
por: Umerez, Maitane, et al.
Publicado: (2017)

In vitro anthracycline cross-resistance pattern in childhood acute lymphoblastic leukaemia.
por: Klumper, E., et al.
Publicado: (1995)

Identification of Metabolic Biomarkers in Relation to Methotrexate Response in Early Rheumatoid Arthritis
por: Gosselt, Helen R., et al.
Publicado: (2020)

Metabolic syndrome detection with biomarkers in childhood cancer survivors
por: Pluimakers, V G, et al.
Publicado: (2020)

MTHFR polymorphism and red cell folate levels are not useful as biomarkers of methotrexate efficacy and toxicity in children with juvenile idiopathic arthritis
por: Tuková, J, et al.
Publicado: (2008)

Folate catabolism in tumour-bearing rats and rats treated with methotrexate.
por: Saleh, A. M., et al.
Publicado: (1981)

A Study on Prevalence and Determinants of Ototoxicity During Treatment of Childhood Cancer (SOUND): Protocol for a Prospective Study
por: Diepstraten, Franciscus A, et al.
Publicado: (2022)

Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity
por: Abedi, Marjan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q32h1pd84tgt9u2pohagl76qj8