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Network-based method for regions with statistically frequent interchromosomal interactions at single-cell resolution

BACKGROUND: Chromosome conformation capture-based methods, especially Hi-C, enable scientists to detect genome-wide chromatin interactions and study the spatial organization of chromatin, which plays important roles in gene expression regulation, DNA replication and repair etc. Thus, developing comp...

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Detalles Bibliográficos
Autores principales: Bulathsinghalage, Chanaka, Liu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526258/
https://www.ncbi.nlm.nih.gov/pubmed/32998686
http://dx.doi.org/10.1186/s12859-020-03689-x