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Network-based method for regions with statistically frequent interchromosomal interactions at single-cell resolution
BACKGROUND: Chromosome conformation capture-based methods, especially Hi-C, enable scientists to detect genome-wide chromatin interactions and study the spatial organization of chromatin, which plays important roles in gene expression regulation, DNA replication and repair etc. Thus, developing comp...
Autores principales: | Bulathsinghalage, Chanaka, Liu, Lu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526258/ https://www.ncbi.nlm.nih.gov/pubmed/32998686 http://dx.doi.org/10.1186/s12859-020-03689-x |
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