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Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol

Cardiac energetic dysfunction has been reported in patients with type 2 diabetes (T2D) and is an independent predictor of mortality. Identification of the mechanisms driving mitochondrial dysfunction, and therapeutic strategies to rescue these modifications, will improve myocardial energetics in T2D...

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Detalles Bibliográficos
Autores principales: Kerr, Matthew, Miller, Jack J., Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N., Aparicio, Claudia N. Montes, Scott, Iain, Tyler, Damian J., Heather, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526448/
https://www.ncbi.nlm.nih.gov/pubmed/32879143
http://dx.doi.org/10.1172/jci.insight.140326