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Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol
Cardiac energetic dysfunction has been reported in patients with type 2 diabetes (T2D) and is an independent predictor of mortality. Identification of the mechanisms driving mitochondrial dysfunction, and therapeutic strategies to rescue these modifications, will improve myocardial energetics in T2D...
Autores principales: | Kerr, Matthew, Miller, Jack J., Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N., Aparicio, Claudia N. Montes, Scott, Iain, Tyler, Damian J., Heather, Lisa C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526448/ https://www.ncbi.nlm.nih.gov/pubmed/32879143 http://dx.doi.org/10.1172/jci.insight.140326 |
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