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Regulator combinations identify systemic sclerosis patients with more severe disease

Systemic sclerosis (SSc) is a heterogeneous autoimmune disorder that results in skin fibrosis, autoantibody production, and internal organ dysfunction. We previously identified 4 “intrinsic” subsets of SSc based upon skin gene expression that are found across organ systems. Gene expression regulator...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Franks, Jennifer M., Yang, Monica, Toledo, Diana M., Wood, Tammara A., Hinchcliff, Monique, Whitfield, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526449/
https://www.ncbi.nlm.nih.gov/pubmed/32721949
http://dx.doi.org/10.1172/jci.insight.137567