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Epigenetic regulation of the PGE(2) pathway modulates macrophage phenotype in normal and pathologic wound repair

Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigenetic alterations play a critical role in establishing...

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Detalles Bibliográficos
Autores principales: Davis, Frank M., Tsoi, Lam C., Wasikowski, Rachael, denDekker, Aaron, Joshi, Amrita, Wilke, Carol, Deng, Hongping, Wolf, Sonya, Obi, Andrea, Huang, Steven, Billi, Allison C., Robinson, Scott, Lipinski, Jay, Melvin, William J., Audu, Christopher O., Weidinger, Stephan, Kunkel, Steven L., Smith, Andrew, Gudjonsson, Johann E., Moore, Bethany B., Gallagher, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526451/
https://www.ncbi.nlm.nih.gov/pubmed/32879137
http://dx.doi.org/10.1172/jci.insight.138443