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Epigenetic regulation of the PGE(2) pathway modulates macrophage phenotype in normal and pathologic wound repair
Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigenetic alterations play a critical role in establishing...
Autores principales: | Davis, Frank M., Tsoi, Lam C., Wasikowski, Rachael, denDekker, Aaron, Joshi, Amrita, Wilke, Carol, Deng, Hongping, Wolf, Sonya, Obi, Andrea, Huang, Steven, Billi, Allison C., Robinson, Scott, Lipinski, Jay, Melvin, William J., Audu, Christopher O., Weidinger, Stephan, Kunkel, Steven L., Smith, Andrew, Gudjonsson, Johann E., Moore, Bethany B., Gallagher, Katherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526451/ https://www.ncbi.nlm.nih.gov/pubmed/32879137 http://dx.doi.org/10.1172/jci.insight.138443 |
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