Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

In order to prioritize available immune therapeutics, immune profiling across glioma grades was conducted, followed by preclinical determinations of therapeutic effect in immune-competent mice harboring gliomas. T cells and myeloid cells were isolated from the blood of healthy donors and the blood a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ott, Martina, Tomaszowski, Karl-Heinz, Marisetty, Anantha, Kong, Ling-Yuan, Wei, Jun, Duna, Maya, Blumberg, Katia, Ji, Xiaorong, Jacobs, Carmen, Fuller, Gregory N., Langford, Lauren A., Huse, Jason T., Long, James P., Hu, Jian, Li, Shulin, Weinberg, Jeffrey S., Prabhu, Sujit S., Sawaya, Raymond, Ferguson, Sherise, Rao, Ganesh, Lang, Frederick F., Curran, Michael A., Heimberger, Amy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526457/
https://www.ncbi.nlm.nih.gov/pubmed/32721947
http://dx.doi.org/10.1172/jci.insight.134386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526457/
https://www.ncbi.nlm.nih.gov/pubmed/32721947
http://dx.doi.org/10.1172/jci.insight.134386

Ejemplares similares