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IL-10 provides cardioprotection in diabetic myocardial infarction via upregulation of Heme clearance pathways

Diabetes is a risk factor for myocardial infarction, and outcomes after myocardial infarction are worse among diabetics compared with nondiabetics. Diabetes is associated with impaired Heme clearance. Here, we determined whether heme toxicity and impaired heme clearance contribute to diabetic myocar...

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Detalles Bibliográficos
Autores principales: Gupta, Rajesh, Liu, Lijun, Zhang, Xiaolu, Fan, Xiaoming, Krishnamurthy, Prasanna, Verma, Suresh, Tongers, Jörn, Misener, Sol, Ashcherkin, Nikita, Sun, Hongliu, Tian, Jiang, Kishore, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526458/
https://www.ncbi.nlm.nih.gov/pubmed/32879134
http://dx.doi.org/10.1172/jci.insight.133050