Cardiomyocyte adhesion and hyperadhesion differentially require ERK1/2 and plakoglobin

Arrhythmogenic cardiomyopathy (AC) is a heart disease often caused by mutations in genes coding for desmosomal proteins, including desmoglein-2 (DSG2), plakoglobin (PG), and desmoplakin (DP). Therapy is based on symptoms and limiting arrhythmia, because the mechanisms by which desmosomal components...

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Detalles Bibliográficos
Autores principales: Shoykhet, Maria, Trenz, Sebastian, Kempf, Ellen, Williams, Tatjana, Gerull, Brenda, Schinner, Camilla, Yeruva, Sunil, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526536/
https://www.ncbi.nlm.nih.gov/pubmed/32841221
http://dx.doi.org/10.1172/jci.insight.140066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526536/
https://www.ncbi.nlm.nih.gov/pubmed/32841221
http://dx.doi.org/10.1172/jci.insight.140066

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