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Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys

African green monkeys (AGMs) are natural hosts of SIV that postthymically downregulate CD4 to maintain a large population of CD4(–)CD8aa(+) virus-resistant cells with Th functionality, which can result in AGMs becoming apparently cured of SIV(agm) infection. To understand the mechanisms of this proc...

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Detalles Bibliográficos
Autores principales:	Mudd, Joseph C., Lai, Stephen, Shah, Sanjana, Rahmberg, Andrew, Flynn, Jacob K., Starke, Carly E., Perkins, Molly R., Ransier, Amy, Darko, Sam, Douek, Daniel C., Hirsch, Vanessa M., Cameron, Mark, Brenchley, Jason M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526541/ https://www.ncbi.nlm.nih.gov/pubmed/32841214 http://dx.doi.org/10.1172/jci.insight.139043

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