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IL-32γ potentiates tumor immunity in melanoma

Myeloid cells orchestrate the antitumor immune response and influence the efficacy of immune checkpoint blockade (ICB) therapies. We and others have previously shown that IL-32 mediates DC differentiation and macrophage activation. Here, we demonstrate that IL-32 expression in human melanoma positiv...

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Detalles Bibliográficos
Autores principales: Gruber, Thomas, Kremenovic, Mirela, Sadozai, Hassan, Rombini, Nives, Baeriswyl, Lukas, Maibach, Fabienne, Modlin, Robert L., Gilliet, Michel, von Werdt, Diego, Hunger, Robert E., Seyed Jafari, S. Morteza, Parisi, Giulia, Abril-Rodriguez, Gabriel, Ribas, Antoni, Schenk, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526542/
https://www.ncbi.nlm.nih.gov/pubmed/32841222
http://dx.doi.org/10.1172/jci.insight.138772