Granzyme A–producing T helper cells are critical for acute graft-versus-host disease

Acute graft-versus-host disease (aGVHD) can occur after hematopoietic cell transplant in patients undergoing treatment for hematological malignancies or inborn errors. Although CD4(+) T helper (Th) cells play a major role in aGVHD, the mechanisms by which they contribute, particularly within the int...

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Detalles Bibliográficos
Autores principales: Park, Sungtae, Griesenauer, Brad, Jiang, Hua, Adom, Djamilatou, Mehrpouya-Bahrami, Pegah, Chakravorty, Srishti, Kazemian, Majid, Imam, Tanbeena, Srivastava, Rajneesh, Hayes, Tristan A., Pardo, Julian, Janga, Sarath Chandra, Paczesny, Sophie, Kaplan, Mark H., Olson, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526544/
https://www.ncbi.nlm.nih.gov/pubmed/32809971
http://dx.doi.org/10.1172/jci.insight.124465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526544/
https://www.ncbi.nlm.nih.gov/pubmed/32809971
http://dx.doi.org/10.1172/jci.insight.124465

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