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Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis

BACKGROUND: Baseline expression of FCRL5, a marker of naive and memory B cells, was shown to predict response to rituximab (RTX) in rheumatoid arthritis. This study investigated baseline expression of FCRL5 as a potential biomarker of clinical response to RTX in granulomatosis with polyangiitis (GPA...

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Detalles Bibliográficos
Autores principales: Owczarczyk, Kasia, Cascino, Matthew D., Holweg, Cecile, Tew, Gaik W., Ortmann, Ward, Behrens, Timothy, Schindler, Thomas, Langford, Carol A., St. Clair, E. William, Merkel, Peter A., Spiera, Robert, Seo, Philip, Kallenberg, Cees G.M., Specks, Ulrich, Lim, Noha, Stone, John, Brunetta, Paul, Prunotto, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526555/
https://www.ncbi.nlm.nih.gov/pubmed/32841219
http://dx.doi.org/10.1172/jci.insight.136180