Human Tregs at the materno-fetal interface show site-specific adaptation reminiscent of tumor Tregs

Tregs are crucial for maintaining maternal immunotolerance against the semiallogeneic fetus. We investigated the elusive transcriptional profile and functional adaptation of human uterine Tregs (uTregs) during pregnancy. Uterine biopsies, from placental bed (materno-fetal interface) and incision sit...

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Detalles Bibliográficos
Autores principales: Wienke, Judith, Brouwers, Laura, van der Burg, Leone M., Mokry, Michal, Scholman, Rianne C., Nikkels, Peter G.J., van Rijn, Bas B., van Wijk, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526557/
https://www.ncbi.nlm.nih.gov/pubmed/32809975
http://dx.doi.org/10.1172/jci.insight.137926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526557/
https://www.ncbi.nlm.nih.gov/pubmed/32809975
http://dx.doi.org/10.1172/jci.insight.137926

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